As a researcher I love to read. I do prefer some light reading, but on occasion I do try to read a research article, or two. I recently came across a publication that was of interest… is it an Autoimmune or Autoinflammatory disease?
So let’s begin with a little primer on AS for those of you who do not understand what this disease is.
Most people, including some doctors, believe that AS is an autoimmune disease (AD), which it is not. It is considered a chronic inflammatory disease or autoinflammatory disease (AID). AID and AD both result from the immune system attacking the body’s own tissues. Both of these disorders also cause inflammation. However, in AID the immune system causes inflammation for unknown reasons, whereas in AD the immune system mistakenly reacts with the body’s own cellular components as if they were foreign antigens. AIDs also have a hereditary component usually associated with a gene mutation.  [²] Autoinflammatory diseases is a new group, since 1999, of rare hereditary immune-mediated disorders that share similar features, but I have found that some of these features are controversial depending who you are talking to.
At one time, way back in the beginning, AS was labeled as an autoimmune disease, but researchers began looking at self-directed tissue inflammation and said “wait this isn’t autoimmune in nature”. Well they didn’t really say that but that is what I was thinking as I read it. Anyway, with this new category all diseases that were of a self-directed tissue inflammation type were taken out of the “autoimmune” classification and put in the “autoinflammatory”. Along with this new information they had problems with another weakness in the concept of autoimmunity: the idea that the immune system functions by making a distinction between self and nonself has come under scrutiny for failing to explain a number of findings. For example, why can’t the body tell that a tumor is a foreign invader?
There have been several studies completed in the past that dispels the idea that AS is just an inflammatory disease but in fact an autoimmune disease. 3 One study even suggested that AS was in fact a Mixed pattern diseases, meaning it has both AIDs and AD characteristics.4
So what do you think? I know the medical community is grasping at straws. Everything has to be in a category. So my question is “who cares if it’s an autoimmune or an autoinflammatory?” Why can’t doctors find the root of the inflammation, since both of these types of diseases obviously center on inflammation?
I am sticking to what I know about both of these diseases and that is the inflammation is killing us slowly! So I will continue to do what I have been doing, trying to find the root source of my inflammation. Try it yourself and see if you get any better result than your doctor can!
- Check for hidden infections — yeast, viruses, bacteria, Lyme, etc. — with the help of a doctor, and treat them.
- Check for hidden food allergens with immunoglobulin G (IgG) food testing, biofeedback, or muscle testing.
- Get checked for heavy metal toxicity. Mercury and other metals can cause autoimmunity.
- Fix your gut.
- Use nutrients such as fish oil, vitamin C, vitamin D, and probiotics to help calm your immune response naturally.
- Exercise regularly — it’s a natural anti-inflammatory.
- Practice deep relaxation like yoga, deep breathing, biofeedback, or massage, because stress worsens the immune response.